FAQs

What do we analyze in your DNA?

We analyze what makes you different, to be precise, we analyze the most common known variations among humans called SNPs (Single Nucleotide Polymorphisms). A SNP is a genetic marker, that is, a position in your DNA associated with certain phenotypes; we analyze 750,000 of this genetic markers.

 
SNPs

What technology do we use?

In ADNTRO we use the Illumina chip “GSA array” which is a collection of microscopic DNA points attached to a solid surface. Scientists use DNA microarrays to measure expression levels of large numbers of genes simultaneously.

Where is my sample sent?

It is shipped directly to the laboratory, which is in Denmark and which is prepaid with our Home-kit. DNA is extracted from your sample and then genotyped using a technology called micro-arrays.

How accurate are my results?

The quality of our RAW data has 99% accuracy of correct genotypes; when there is a doubt a “NC” appears in your data, meaning “no call” if the genotype did not pass the accuracy threshold pre-defined.

Additionally, our algorithms compare your sample with a public database known as 1000 Genome, currently being used as the reference in the design of micro-arrays. This comparison allows us to offer you a relative result of your reference population (e.g. European population) and determine your predisposition to certain traits in relative terms.

What is genetic predisposition?

Genetic predisposition or genetic susceptibility means the genetic mass capable of influencing the phenotype of a person, population or species. The phenotype is known as the expression of the environmental-dependent genotype (DNA). It is the visible manifestation of the genotype and refers to any characteristic or trait of a person; involves morphology, physiology, behavior, biochemical properties, etc.

Therefore, genetic predisposition is the increase or decrease in the likelihood of disease depending on the genetics. Through SNPs and following a multiplicative mathematical model with exceptions such as haplotypes, it is possible to calculate the risk that a particular person could have in the development of a disease, using the incidence and allele Frequencies.

 

If you have further questions, register and watch our explanatory videos